Abdominal pain, feeling of heaviness, bloating?* Trimedat® helps to eliminate several symptoms at once* by acting on the cause of their appearance**

Dosage form
Tablets, powder for suspension preparation
Active substance
Tablets – trimebutin maleate Powder for suspension preparation – trimebutin
For children from 3 years old: 100 mg tablets No. 10, powder for suspension preparation. For adults and children from 12 years: 200 mg tablets No. 30, 300 mg tablets No. 20 and No. 60

Stress, intestinal infections and/or malnutrition combined with a hereditary predisposition can lead to the development of functional diseases of the gastrointestinal tract.

Such diseases can manifest themselves in various symptoms or even a complex of symptoms, including:

  • abdominal pain,
  • bloating,
  • heaviness,
  • stool disorders (constipation, diarrhea or their alternation)1.

The cause of these symptoms, in most cases, is a violation of the motility of the digestive tract and its increased sensitivity.

Trimedate ® acts throughout the gastrointestinal tract, including the biliary tract, and has a triple mechanism of action2:

  • relieves gastrointestinal spasms,
  • restores the natural rhythm of the gastrointestinal motility,
  • normalizes hypersensitivity of the gastrointestinal tract.

Thus, Trimedat ® simultaneously works with multidirectional motor disorders and helps to eliminate a complex of symptoms: pain, discomfort, heaviness and bloating in the abdomen, as well as stool disorders (constipation, diarrhea or their alternation)1.

Trimedat ® does not mask symptoms, but acts on the causes of their occurrence - impaired motor skills and increased sensitivity of the gastrointestinal tract, therefore helps to prevent their reappearance in the future2.

Professional recognition of Trimedat ®
  • Winner of the IV Russian Pharma Awards 2015, 2017, 2021, 2023 "Drug of choice among antispasmodics" (according to the results of online voting of doctors).Website:
  • Winner of the award "Brand No. 1 in Russia ® 2020" in the category "Symptomatic drug for the treatment of gastrointestinal tract" (according to the results of online voting of consumers). Website:
  • The most prescribed drug in the category of antispasmodics and prokinetics.***
  • The active substance Trimedat ® – trimebutin – is included in a large number of clinical recommendations:

Clinical recommendations of the Russian Gastroenterological Association:

  • Gastritis and duodenitis
  • Irritable bowel syndrome
  • Functional dyspepsia
  • Biliary dyskinesia
  • Gastroesophageal reflux disease
  • Cholelithiasis

Roman Criteria IV (section on dyskinesia of Oddi's sphincter)

Clinical recommendations of the RNMOT and the Scientific Society of Gastroenterologists of Russia

  • Chronic diarrhea in adults

Methodological recommendations of the Russian Scientific Medical Society of Therapists

  • Features of the course of Long-COVID infection, therapeutic and rehabilitation measures

Clinical recommendations of the Union of Pediatricians of Russia

  • Gastroesophageal reflux disease in children

Recommendations of the Russian Society of Pediatric Gastroenterologists, Hepatologists and Nutritionists

  • Functional disorders of the digestive organs in children
* With functional diseases of the gastrointestinal tract (gastrointestinal tract) and biliary tract.

** The cause of the symptoms of functional diseases of the gastrointestinal tract and biliary tract is motor disorders and sensitivity of the gastrointestinal tract and biliary tract.

1 Instruction for use No 002527.

2 Yakovenko E. P. et al . Agonist of opiate receptors trimebutin in the therapy of functional disorders of the gallbladder and sphincter Oddi //Journal "Attending Physician" No02/2014.

*** According to the Prindex study "Monitoring of prescriptions of medicines" by Ipsos Healthcare, the Trimedat ® brand, according to the results of the 4th quarter of 2023, ranks first in the recommendations of specialists in 14 cities of the Russian Federation among medicines from the ATS groups of AOSA Synthetic antispasmodics and holinoblockers and AOSA Gastrointestinal motility stimulants.